In cutting-edge scientific research, precision is the foundation of discovery. As demands rise for ultra-miniaturized, cost-efficient, and high-throughput workflows, picoliter liquid dispensing has emerged as a transformative tool. At PolyPico Technologies, we provide researchers with the ability to precisely dispense picoliter to nanoliter volumes, enabling ultra-sensitive assays, significantly reducing reagent waste, and maximizing accuracy across diverse application areas—from biotech and diagnostics to materials science and drug development.
Whether developing high-density biochips, next-gen biosensors, or conducting high-throughput drug screening, PolyPico’s piezo-based non-contact microdispensing systems are designed to elevate performance, increase efficiency, and support scalable innovation at every stage of R&D.
Why Picoliter Precision Matters More Than Ever
As research continues to move toward higher throughput and tighter budgets, scientists need tools that optimize resources without compromising data integrity. PolyPico’s precision dispensing systems, capable of delivering as little as 10 pL of liquid with high repeatability, support these demands.
Key benefits of picoliter dispensing with PolyPico include:
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Unmatched Accuracy – Consistent, repeatable droplet deposition down to 10 pL.
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High Density Arrays – Dispense thousands of droplets in compact formats, ideal for microarrays and lab-on-chip designs.
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True Non-Contact Dispensing – Prevent cross-contamination and protect sample integrity.
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Scalable Automation – Seamlessly scale from early-stage prototyping to full-volume production.
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Sample and Reagent Efficiency – Reduce waste and conserve costly or limited materials.
Application Spotlight #1: Biosensors for Diagnostics & Environmental Monitoring
Biosensors are now integral to real-time diagnostics and environmental surveillance. From detecting pathogens in human samples to identifying contaminants in soil and water, the sensitivity and specificity of biosensors rely on the precise placement of detection reagents—an area where PolyPico excels.
For instance, PolyPico’s technology enables the exact deposition of biorecognition molecules onto sensor substrates at picoliter resolution. This ensures reliable performance and reproducibility, even when handling highly sensitive targets like CRISPR-based DNA probes or antibodies.
Why PolyPico?
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Enhanced sensitivity through accurate molecule placement
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Consistent, high-throughput fabrication of sensor elements
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Compatibility with a wide range of biological, aqueous, and organic fluids
Application Spotlight #2: High-Density Microarrays and Biochips
Microarrays require precise spotting of thousands of probes onto substrates to analyze gene expression, protein interactions, or immune responses. With PolyPico’s piezo-electric microdispensers, researchers can confidently deposit bio-reagents with extreme positional accuracy and volume control—making complex multiplexed assays not only possible but routine.
Recent studies leveraging picoliter-scale spotting have enabled ultra-compact arrays, allowing researchers to assess numerous biomarkers simultaneously while conserving critical reagents and samples. With PolyPico, you can:
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Increase array density without sacrificing consistency
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Print on a variety of substrates, including glass, membranes, and microfluidic chips
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Scale from prototype to production using the same core dispensing platform
Application Spotlight #3: Drug Discovery and Screening
In pharmaceutical R&D, the costs of screening large compound libraries and performing cellular assays can be immense—especially when reagent volumes are not tightly controlled. PolyPico dispensing systems solve this with ultra-low volume, non-contact delivery that ensures every drop is accurate and accounted for.
With sub-nanoliter to picoliter precision, our technology supports dose-response experiments, high-content screening, and live-cell dispensing with minimal shear stress. This empowers scientists to:
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Lower assay costs with ultra-efficient reagent usage
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Minimize variability for reproducible drug screening
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Handle viscous or shear-sensitive samples with confidence
Enabling the Future of Scientific Innovation
PolyPico’s modular, compact, and highly customizable dispensing systems are designed to adapt to your workflow—from benchtop research to integrated industrial solutions. With the capability to handle aqueous, organic, and biologically active materials, our technology supports advanced applications in diagnostics, materials research, and bioengineering.
With no dead volume, digital control, and real-time monitoring, PolyPico systems deliver reliability and flexibility to match your evolving needs.
Discover What’s Possible with PolyPico
Whether you’re pioneering a new diagnostic platform, designing next-gen biosensors, or conducting high-throughput screening, PolyPico gives you the precision, scalability, and support to accelerate your research.
Let’s build the future of science—one picoliter at a time.
To schedule a 30-minute demo click here: https://lnkd.in/e2Aw_iQS to explore our dispensing solutions or contact us to discuss your specific application needs.
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