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Polypico systems, used in breakthrough Neutrophil research

Neutrophil infiltration into inflamed and infected tissues is a fundamental process of the innate immune response.

While neutrophil interactions with the blood vessel wall have been intensely studied over the last decades, neutrophil dynamics beyond the vasculature have for a long time remained poorly investigated.

But that is changing, and recent research is revealing new insights about neutrophil responses within tissues. For example, neutrophils form swarms to attack pathogens including bacteria, parasites ,and fungi.

In this study, enabled by Polypico systems, the researchers designed an assay for studying neutrophil’s ability to contain clusters of live Candida.

Read the full story on https://www.nature.com/articles/s41467-020-15834-4

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